Nitenpyram is used orally with dogs and cats to control fleas. After ingestion, it begins killing fleas within 30
minutes and kills all adult fleas within 4 hours.
The effects of nitenpyram last approximately 24–48 hours.
Nitenpyram is safe to use on puppies and kittens as young as four weeks old if they weigh at least 2 pounds (0.91 kg).
Panting and excitement have been noted in cats within 2 hours of administration.
In heavily infested animals, it can cause extreme itching as the fleas die.